There are many myths and misconceptions about what high THC cannabis and other Cannabinoids do to the body and brain. But the truth is that they do affect both. The chemical structure of THC is very similar to another chemical produced by the brain, anandamide. Because of this, THC and the body can recognize each other and alter communication. This makes cannabis such a popular recreational drug. But is it really that good?
Cannabinoids And The Endocannabinoid Systems
Cannabinoids are chemical messengers in the human brain that regulate the various functions of the nervous system. Cannabinoids are produced in the neuron from lipid precursors, travel across the synapse, and attach to receptors on nearby neurons. This way, they are able to send signals to other neurons, which regulates their activity. Consequently, marijuana may have some benefits for the body.
Endocannabinoids have many physiological roles, including regulation of the immune system. When an imbalance in the immune system is present, the endocannabinoid system reacts by releasing cannabinoids. Inhibitors of FAAH and MAGL have demonstrated beneficial effects in stimulating the ECS and blocking the degradation of endo/phyto-cannabinoids. Therefore, cannabinoids can be an effective alternative for opioids and benzodiazepines.
The human endocannabinoid system regulates cellular proliferation, differentiation, and tissue invasion. It also modulates angiogenesis. These qualities make the ECS an essential part of most cancer treatments. Studies have shown that cannabinoids also have beneficial effects for cancer patients, such as reducing nausea and vomiting. Further, these substances may have anti-cancer properties. The ability to modulate gene expression by blocking or inhibiting the production of certain cancer cells is one of the benefits of cannabinoids.
The Receptors For Cannabinoids Are Widely Distributed Throughout The Body
They are embedded in cell membranes, and stimulation of these receptors can affect a range of physiological processes. Researchers have identified two cannabinoid receptors, the CB1 and CB2, which are most abundant in the nervous system and immune system. Cannabinoids also affect the EC system by modulating several essential biological processes.
Although cannabis research has been prohibited for decades, it is possible to supplement your diet with cannabinoids to boost the body’s own cannabinoids. CBD does not produce any intoxicating effects, so you won’t get a high or become euphoric after consuming it. You can also take CBD oil or other cannabinoid-containing products. The CBD oil in particular has anti-inflammatory properties, which help your body fight off disease and chronic illnesses.
Cannabis Affects The Endocannabinoid Systems
Scientists studying the effects of marijuana have made several important discoveries. For one, they’ve identified the active ingredient in marijuana, called delta-9-tetrahydrocannabinol. They also discovered where and how the substance works in the brain. They named this system the endocannabinoid system, after the marijuana plant. Scientists now know that THC affects certain parts of the EC system, affecting memory, addiction, and many other important functions.
Several Endocannabinoid Systems Are Involved In Regulating Vital Bodily Functions
Endocannabinoids, which are naturally occurring lipid-based neurotransmitters, help regulate several functions in the human body. Although their functions are not fully understood, they’re thought to help the body manage different bodily processes. Cannabis affects the EC system in two ways. First, cannabis acts as a neurotransmitter by attaching to cannabinoid receptors on the surface of various cells in the body.
Second, cannabis inhibits FAAH, a gene that controls the production of a hormone known as 2-AG. While FAAH plays a major role in MDD, it also helps prevent the disease. This is because CBD inhibits FAAH and increases AEA levels. This process is also important in the regulation of brain inflammation and edema. Lastly, cannabis affects the EC system through various mechanisms.
Third, the EC system influences the heart’s function. Studies have shown that chronic cannabis use can cause atrial fibrillation, atrial ischemia, and ventricular tachycardia. Chronic use of cannabis has also been linked to limb ischemia and acute thrombosis of the aorta. The study’s authors question the role of the EC in the development of stress cardiomyopathy.
Further, cannabis inhibits the expression of endocannabinoids in the brain, which are responsible for controlling body temperature. The ECS is located throughout the body, and scientists have yet to discover all the functions of endocannabinoids in the body. It also affects our appetite and regulates our body’s temperature. The ECS may be the target of multiple promising therapeutics. They produce endocannabinoids, which are of great medical interest.